what causes dupuytren's contracture

© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). The condition affects a layer of tissue that lies under the skin of your palm.

They include: The condition usually runs in families, which means it is inherited. Dupuytren's (du-pwe-TRANZ) contracture is a hand deformity that usually develops over years. If you have this condition, you may also find it difficult to place your hand flat on the table, wear gloves, or shake hands, among other things.These exams and tests will be repeated over time to determine if the condition is getting worse.There is no cure for Dupuytren's contracture. Dupuytren’s contracture happens when tissue thickens and tightens under the palm, pulling at least one finger in toward the middle of the hand. But as Dupuytren's contracture progresses, it can limit your ability to fully open your hand, grasp large objects or to get your hand into narrow places.Mayo Clinic does not endorse companies or products. Since the thumb and index finger aren't usually affected, many people don't have much inconvenience or disability with fine motor activities such as writing. Complications of Dupuytren's contracture surgery are rare but may include:You will have some hand swelling and discomfort after the procedure. All rights reserved. You are also more likely to develop this condition if you have a Northern European (English, Irish, Scottish, French, Dutch) or Scandinavian (Swedish, Norwegian, Finnish) background.Dupuytren's contracture is more common in men than women, particularly those over age 40.Your chances of developing it increase as you get older.The first symptom for many patients is one or more lumps (nodules) under the skin in the palm of the hand. Dupuytren's contracture is a condition in which one or more fingers become permanently bent in a flexed position.

A firm lump of tissue can form on your palm. It results from a thickening and scarring of connective tissue under the skin in the palm of the hand and in the fingers.Dupuytren's (du-pwe-TRANZ) contracture is a hand deformity that usually develops over years.

As these cords tighten, your fingers might be pulled toward your palm, sometimes severely.The two fingers farthest from the thumb are most commonly affected, though the middle finger also can be involved. Dupuytren's contracture is an abnormal thickening and tightening of the normally elastic tissue beneath the skin of the palm and fingers.

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The most common side effects seen with Xiaflex are swelling, bleeding, bruising, or pain at the injection site. You might need a series of shots to see long-term results.Xiaflex), a mixture of enzymes that help dissolve the thick and tight tissue, may be injected into the affected area by your doctor.

This weakens the tight bands and may allow your doctor to then stretch the tightened area. Causes and preventing Dupuytren's contracture. Dupuytren Disease and the associated Contracture are most often passed on genetically through a faulty gene that seems to have originated in Northern Europe, possibly as far back as during the Viking times.

Dupuytren's contracture (also called Dupuytren disease) is a condition that results in gradual and progressive thickening and shorting of tissue under the skin on the palm (the palmar fascia) and can affect how the fingers move. While typically not painful, some aching or itching may be present.

"American Academy of Family Physicians web site: "Dupuytren's Disease: Diagnosis and Treatment. There are essentially five main causes of Dupuytren’s Contracture: Genetics.

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what causes dupuytren's contracture